e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Discovery of 3-(2, 6-dichloro-3, 5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective …
V Guagnano, P Furet, C Spanka, V Bordas…
Index: Journal of Medicinal Chemistry, , vol. 54, # 20 p. 7066 - 7083
... Journal of ... Introduction. During the past 15 years, the pharmaceutical industry has shown an ever-growing interest in the field of tyrosine kinases. ... The quest for highly selective small molecule inhibitors of specific kinases is still a significant challenge for medicinal chemists. ...