Introduction. Glutamic acid is the major excitatory neurotransmitter in the central nervous system, exerting its actions at multiple subtypes of excitatory amino acid (EAA) receptors. 1 2- Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl) propanoic acid (AMPA) receptors are a subtype of the ligand gated ion channel (ionotropic) family of EAA receptors, which may be composed of assemblies of four different receptor protein subunits, GluR1-4. 2 In addition, ...
