Tetrahedron Letters

From building block to natural products: a short synthesis and complete NMR spectroscopic characterization of (±)-anatabine and (±)-anabasine

T Saloranta, R Leino

Index: Saloranta, Tiina; Leino, Reko Tetrahedron Letters, 2011 , vol. 52, # 36 p. 4619 - 4621

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Citation Number: 9

Abstract

A short and straightforward synthesis of the racemic tobacco alkaloids anatabine and anabasine in five and six steps, respectively, from 3-pyridinecarboxaldehyde utilizing Barbier-type Zn-mediated allylation and ring-closing olefin metathesis, as the key steps, is ...