Highly enantioselective rearrangement of β-amino alcohols was realized by using a catalytic amount of H 2 SO 4 . ... N,N-Dialkyl-β-amino alcohols can rearrange via an aziridinium intermediate when treated with SOCl 2 , [1] SOBr 2 , [2] MsCl, [3] TsCl, [3c] CBr 4 /PPh 3 , [4] Ph 3 PCl 2 , [5] Ph 3 PBr 2 , [5] DEAD/PPh 3 , [3b] [6] Ms 2 O, [3b] Tf 2 O, [7] DAST, [8] or Deoxofluor ® . [9] We have previously shown that N,N-dialkyl-β-amino alcohols of type B could be obtained ...
