Pyridine Derivatives. I. 3-Cyano-4-ethoxymethyl-6-methyl-2-pyridone and some related transformation products

WF Bruce, HW Coover Jr

Index: Bruce; Coover Journal of the American Chemical Society, 1944 , vol. 66, p. 2092

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Citation Number: 23

Abstract

The importance of certain pyridine derivatives in biologically active systems has directed our attention to the synthesis and chemical behavior of some substances containing the pyridine nucleus. Because of our interest in the lactone of 2-methyl-3-hydroxy-4-hydroxymethyl-5-car- boxypyridine, as a chick antianemia factor,'we have studied the synthesis of this substance reported by Harris, Stiller and Folkers.* From this study, certain improvements in the ...