Several new 4, 6-diamino-2-substituted 5-nitrosopyrimidines and S-substituted 2- cyanoacetamides were prepared and used as intermediates in the base-catalyzed preparation of a number of 4, 7-diamino-2-substituted N-substituted 6- pteridinecarboxamides. Many of these pteridines were examined for diuretic activity in rats after oral administration. The more active compoundb were those in which the 2 position ...
