A new fluorescence-based assay for high-throughput screening of reactions that couple two organic molecules is described. The assay involves reaction of one substrate containing a tethered fluorophore with a second molecule that is attached to a solid support. A successful coupling process is signaled by fluorescence of the solid support, which can be isolated by either simple centrifugation or filtration. To evaluate this assay in the context of a catalytic ...
![Phosphine,tris[2-(methoxymethyl)phenyl]- Structure](https://image.chemsrc.com/caspic/332/6962-89-6.png)
