e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Design, synthesis and pharmacological evaluation of conformationally restricted N-arylsulfonyl-3-aminoalkoxy indoles as a potential 5-HT6 receptor ligands
RVS Nirogia, R Kambhampati…
Index: Journal of Enzyme Inhibition and Medicinal Chemistry, , vol. 26, # 3 p. 341 - 349
... Journal of Enzyme Inhibition and Medicinal ... on ring A and α-methyl group in the side chain was least active with 46.68% inhibition at 5-HT 6 R. Its analogue 8g, with β-methyl group in the side chain was found to have better binding affinity (74.13% inhibition), indicating that ...
