Tetrahedron Letters

Removal of O-and N-benzyl groups by fungal biotransformation

HL Holland, M Conn, PC Chenchaiah, FM Brown

Index: Holland, Herbert L.; Conn, Morgan; Chenchaiah, P. Chinna; Brown, Frances M. Tetrahedron Letters, 1988 , vol. 29, # 49 p. 6393 - 6394

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Citation Number: 9

Abstract

Reactions were routinely carried out on a Ig scale using normal biotransformation procedures. 4 Details of substrates and conversions are presented in the Table. In all cases, percentage recoveries were high (2 70%) and percentage conversions are based on isolated, purified products. & isabellina efficiently removes the benzyl group from a variety of ethers. It is specific for benzyloxy vs. methoxy cleavage (see entries 4-6), but does not ...