Tetrahedron letters

Intermediacy of α-chloro amides in the basic hydrolysis of α-chloro nitriles to ketones

CS Shiner, AM Fisher, F Yacoby

Index: Shiner, Christopher S.; Fisher, Allison M.; Yacoby, Fred Tetrahedron Letters, 1983 , vol. 24, # 51 p. 5687 - 5690

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Citation Number: 17

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Isolable α-chloro amides are intermediates in the formation of ketones by basic hydrolysis of α-chloro nitriles. Possible mechanisms for the generation of ketones from α-chloro amides are discussed. ... In the present cases the reaction presumably is accelerated by the electron- ...