… -phosphorus heterocycles. Synthesis of phosphorus-containing cannabinoid precursors and a single-crystal analysis of 1, 2, 3, 4-tetrahydro-10-hydroxy-8-n-pentyl-5H- …

…, NS Pantaleo, A McGuffy, D Van der Helm

Index: Rampal, Jang B.; Berlin, K. Darrell; Pantaleo, Nantelle S.; McGuffy, Ann; Helm, Dick van der Journal of the American Chemical Society, 1981 , vol. 103, # 8 p. 2032 - 2036

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Citation Number: 9

Abstract

Abstract: The syntheses of 1, 2, 3, 4-tetrahydro-lO-hydroxy-8-methyl-and 1, 2, 3, 4-tetrahydro- lO-hydroxy-8-n-pentyl-3-phenyl-5H-phosphorino [3, 4-c][llbenzopyran-Sone 3-oxide have been achieved. These precursors of cannabinoid analogues are the first reported in this family of carbon-phosphorus heterocycles. A single-crystal X-ray diffraction analysis of the pentyl derivative confirmed the structure.'H, I3C, and 31P NMR analyses are also ...