New class of mixed cuprate (I) reagents, lithium hetero (alkyl) cuprate (I), which allow selective alkyl group transfer

GH Posner, CE Whitten, JJ Sterling

Index: Posner,G.H. et al. Journal of the American Chemical Society, 1973 , vol. 95, # 23 p. 7788 - 7800

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Citation Number: 210

Abstract

Abstract: Five different alkylhetero (alkyl) cuprate (I) and arylhetero (alkyl) cuprate (I) reagents of the form Het (R)-CuLi have been prepared from the corresponding heterocopper species (Het-Cu) and organolithium reagents (RLi): Het= t-BuO, PhO, t-Bus, PhS, Et2N. The stability of these mixed cuprate reagents follows the order PhS> PhO> t-BuO> t-Bus-Et2N. Of these five, PhS (R) CuLi is most effective for selective conjugate addition and substitution ...