On the Interactions of Alkyl 2??Hydroxycarboxylic Acids with Alkoxysilanes: Selective Esterification of Simple 2??Hydroxycarboxylic Acids

…, SA Barrett, JE Meegan, SL Warriner

Index: Ansell, Richard J.; Barrett, Simon A.; Meegan, Jonathan E.; Warriner, Stuart L. Chemistry - A European Journal, 2007 , vol. 13, # 16 p. 4654 - 4664

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Citation Number: 8

Abstract

Abstract The interactions of a range of monocarboxylic acids with tetramethoxysilane Si (OMe) 4 (TMOS), in methanol (MeOH), have been investigated by using 1 H, 13 C and 29 Si solution-phase NMR spectroscopy and electrospray mass spectrometry (ESMS). Si (OMe) 4 acts as a catalyst/reagent in the selective methylation of 2-hydroxycarboxylic acids (2HOAs) in MeOH at room temperature: glycolic acid, lactic acid and 2-hydroxybutyric acid are ...