Synthesis of juvabione analogues

…, UV Desai, GD Hebbalkar

Index: Mane, Ramchandra B.; Desai, Uday V.; Hebbalkar, Geeta D. Collection of Czechoslovak Chemical Communications, 1988 , vol. 53, # 3 p. 646 - 657

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Citation Number: 3

Abstract

Abstract Alkylation of various β-ketoesters IIIa-d with bis (p-methoxycarbonylphenyl) bromomethane (II) and bis (p-chlorophenyl) bromomethane (VI) followed by cleavage of ethoxycarbonyl group or hydrolysis and esterification gave methoxycarbonylphenyl and chlorophenyl analogues of ar-juvabione, respectively. Condensation of bis (p- methoxycarbonylphenyl) methanol (IX) with isovaleryl and trichloroacetyl chloride gave ...