Asymmetric Synthesis of 2-Alkyl-Perhydroazepines from [5, 3, 0]-Bicyclic Lactams

AI Meyers, SV Downing, MJ Weiser

Index: Kaga, Harumi; Miura, Masakatsu; Orito, Kazuhiko Synthesis, 1989 , # 11 p. 864 - 866

Full Text: HTML

Citation Number: 44

Abstract

... products is based upon their mechanism of formation, 12 which is depicted in Scheme 1. In synthesis of the ... Products A and B are both formed as a 4−10:1 mixture, respectively, 11 with k 2 ... 5a or 5b could not be altered when heated in wet toluene, but addition of p-TsOH caused ...