Journal of the American Chemical Society

Synthesis of isoquinoline acids

FT Tyson

Index: Tyson Journal of the American Chemical Society, 1939 , vol. 61, p. 183

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Citation Number: 23

Abstract

Only two of the seven possible isoquinoline acids have thus far been reported in the literature, ie, the 1-isoquinoline carboxy acid1 and the 5-or 8-isoquinoline carboxy acid. Since the derivatives of the isoquinoline acids may have useful physiological properties, it seemed desirable to proceed to synthesize members of the series not yet reported. The 4- isoquinoline acid was prepared from the readily available 4-bromoisoquinoline3 by ...