Stephen L. Buchwald,**la M. Woods Wannamaker,Ib and Brett T. WatsonlC ... Department of Chemistry Massachusetts Institute of Technology Cambridge, Massachusetts 021 39 Received September 2, I988 ... The use of transition metals in organic synthesis has increased tremendously in recent years.2 The success of transition- metal-based organic synthesis is due in part to the unique ability of the metal to activate ligands to which it is directly bound. Moreover, ...