Synthesis of robalzotan, ebalzotan, and rotigotine precursors via the stereoselective multienzymatic cascade reduction of α, β-unsaturated aldehydes

E Brenna, FG Gatti, L Malpezzi, D Monti…

Index: Yoneda, Ryuji; Santo, Kazunori; Harusawa, Shinya; Kurihara, Takushi Synthesis, 1986 , # 12 p. 1054 - 1055

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Citation Number: 20

Abstract

... reaction conditions also did not provide any significant improvement.(21). figure Scheme 1. Synthesis of Substrates 5a ... treated with pyridine at 90 °C, together with α,β-unsaturated nitrile 12, also its ... prepared according to Scheme 1c. For the regeneration of the NAD(P)H cofactors ...