Palladium-Catalyzed Saegusa–Ito Oxidation: Synthesis of α, β-Unsaturated Carbonyl Compounds from Trimethylsilyl Enol Ethers

…, PL Nguyen, N Lévaray, H Lebel

Index: Lu, Yingdong; Nguyen, Pierre Long; Levaray, Nicolas; Lebel, Heleine Journal of Organic Chemistry, 2013 , vol. 78, # 2 p. 776 - 779

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Citation Number: 15

Abstract

Palladium-catalyzed Saegusa–Ito oxidation of trimethylsilyl enol ethers is possible using Oxone as a stoichiometric oxidant and sodium hydrogen phosphate as a buffer. Cyclic and acyclic enones as well as α, β-unsaturated aldehydes are obtained in good to excellent yields.