e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Carbonylation of Enynes under Hydroformylation Conditions Catalyzed by Rhodium Carbonyl. A New Method for Synthesis of Cyclic Enones
…, T Joh, T Shiohara, S Takahashi
Index: Doyama, Kazuo; Joh, Takashi; Shiohara, Tomoo; Takahashi, Shigetoshi Bulletin of the Chemical Society of Japan, 1988 , vol. 61, # 12 p. 4353 - 4360
The reactivities of 1-buten-3-yne derivatives toward hydroformylation were studied using a rhodium catalyst. Unexpectedly, cyclopentenone derivatives were obtained in moderate yields together with formylsubstituted dienes and unsaturated lactones. This reaction offers a new method for the catalytic synthesis of cyclopentenones. A mechanism for the cyclic carbonylation of enynes is also discussed.
