Tetrahedron letters

Formal total synthesis of the trinorguaiane sesquiterpenes (+/−)-clavukerin A and (+/−)-isoclavukerin

JC Friese, S Krause, HJ Schäfer

Index: Friese, Jan C; Krause, Stefan; Schaefer, Hans J Tetrahedron Letters, 2002 , vol. 43, # 15 p. 2683 - 2685

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Citation Number: 14

Abstract

The trinorguaiane sesquiterpenes clavukerin A 1., and 1 and isoclavukerin 2 3 are marine natural products that have been isolated from the Okinawan soft coral Clavularia koellikeri during a search for biologically active compounds from marine sources. So far three total syntheses of isoclavukerin 3., 4., and and five total syntheses of clavukerin A have been described, 4., , , 5., , and including three enantiocontrolled routes and two for the racemate. ... Honda et al., 5c Asaoka et al. ...