Synthesis and study of nucleic acids interactions of novel monomethine cyanine dyes

…, I Crnolatac, N Lesev, I Piantanida, T Deligeorgiev

Index: Kaloyanova, Stefka; Crnolatac, Ivo; Lesev, Nedyalko; Piantanida, Ivo; Deligeorgiev, Todor Dyes and Pigments, 2012 , vol. 92, # 3 p. 1184 - 1191

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Citation Number: 10

Abstract

Six asymmetric monomethine cyanine dyes have been synthesized and their spectral characteristics and interaction with double stranded (ds) DNA have been investigated for their prospective use as fluorescent markers in molecular biology. Therefore, the non- covalent binding of the compounds with dsDNA was explored. Apart from the fluorescence spectroscopy, the study includes UV/Vis spectrophotometry and circular dichroism ...