Potential Anticancer Agents. 1 VII. Synthesis and Ammonolysis of Methyl 2, 3-Anhydro-D-ribofuranoside

CD Anderson, L Goodman…

Index: Anderson et al. Journal of the American Chemical Society, 1958 , vol. 80, p. 5247,5250

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Citation Number: 48

Abstract

The synthesis of XI has as its starting material the readily available 1, 2-O-isopropylidene-~- xylofuranosea (I). This was converted to crystalline 1, 2-0-isopropylidene-5-0- methoxycarbonyl-D-xylofuranose (11) by reaction with an excess of methyl chloroformate in pyridine, a procedure that takes advantage of the large difference in rate of