The Journal of Organic Chemistry

Synthesis of Potential Anticancer Agents. XIII. Alkyleniminoquinoxalines1, 2

WR Vaughan, MS Habib

Index: Vaughan,W.R.; Habib,M.S. Journal of Organic Chemistry, 1962 , vol. 27, p. 324 - 327

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Citation Number: 2

Abstract

To this end 2, 3-dichloroquinoxaline (I) 4 and 2-chloro-3-methylquinoxaline (11) 6 were prepared and used as primary starting materials for condensation with appropriate alkylenimines. The two active chlorines of I permitted the introduction of either one such substituent (111-VII) or two (similar or different) substituents (XII-XXV). Data are assembled in Table I. In addition a quinoxaline carrying a nitrogenmustard function was prepared by ...