Biomolecules Bearing the SAsMe2 Group: Nucleoside Derivatives

NLM Dereu, RA Zingaro

Index: Dereu; Zingaro Bulletin des Societes Chimiques Belges, 1982 , vol. 91, # 8 p. 685 - 694

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Citation Number: 4

Abstract

INTRODUCTION Biomolecules having the general formula GXAsR2 have been the subject of a num- ber of studies during the past seven years. In these compounds, X is S or Se and derivatives have been prepared in which G is a monosaccharidela or an amino acid or di- or tripeptidelb. At the present, 22 of these derivatives have been found to be active ( % T/C - 125) against mouse leukemias in in vivo testing (PS388 and L1210 test systems). These ...