Synthesis using allylidenedihydropyridines. 9. First preparation of thiino [3, 2-a] indolizine derivatives

A Kakehi, S Ito, T Ohizumi, T Maeda

Index: Kakehi, Akikazu; Ito, Suketaka; Ohizumi, Tsuyoshi; Maeda, Toshiaki Journal of Organic Chemistry, 1982 , vol. 47, # 2 p. 369 - 371

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Citation Number: 8

Abstract

E 8 COOE t B z COPh fluorescence were formed. For example, the treatment of 16 with concentrated hydrochloric acid followed by neutralization with base gave an orange product 24, mp 142-145 OC, in 67% yield. The same compound 24 was also formed by the reaction of 18 in which only the 2-alkylthio group was different from that of 16. Similar treatment of indolizines 17 and 19-22 yielded compounds 25-29 in 4043% yields, respectively. On the ...