Abstract: 1-Pent-3-ynyl triflate (lb) was solvolyzed (25 OC, 24 h) in ethanol-water with 2, 6- lutidine as the buffer. Products were formed predominantly (97-98.5%) through direct substitution (k, processes) and elimination. As the water content increases, the yields of 2- methylcyclobutanone (7b)(formed through kA processes) also increase from 0.2%(100% ethanol) to 2.8%(50% ethanol). 1-Pent-3-ynyl triflate was solvolyzed in anhydrous ...
