Journal of the American Chemical Society

Chromanones, Thiochromanones and 2, 3-Dihydro-4 (1H)-quinolones

CD Hurd, S Hayao

Index: Hurd; Hayao Journal of the American Chemical Society, 1954 , vol. 76, p. 5065,5067

Full Text: HTML

Citation Number: 31

Abstract

Polyphosphoric acid is an effective reagent for bringing about the ring closure of 3- aryloxypropionic acids into 4-chromanones, 3-arylmercaptopropionic acids into 4- thiochromanones and r\ i', r\'-diaryl-P-alanines into 2, 3-dihydro-l-aryl-4 (1H)-quinolones. Phosphoryl chloride causes cyclization of Sp-chloro-and Sp-bromophenyl-Sp-tolylsulfonyl- L3-alanine into 6-halo-2, 3-dihydro-lp-tolylsulfonyl-4 (1H)-quinolone but the yields are low ...