e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Effect of a hydrogen bonding carboxamide group on universal bases
…, DM Brown, P Holliger, D Loakes
Index: Too, Kathleen; Brown, Daniel M.; Holliger, Philipp; Loakes, David Collection of Czechoslovak Chemical Communications, 2006 , vol. 71, # 6 p. 899 - 911
Abstract A number of aromatic universal base analogues have been described in the literature, but most are non-hydrogen bonding. We have examined the effect of introducing hydrogen bonding carboxamide groups onto the pyrrole ring of 5-nitroindole. The modified analogues retain universal base features, but there are no overall effects on duplex stability. This leads to the suggestion that the nitro group is within the hydrogen bonding face of the ...
