Convenient Method for Reduction of CN Double Bonds in Oximes, Imines, and Hydrazones Using Sodium Borohydride–Raney Ni System

Y Yang, S Liu, J Li, X Tian, X Zhen…

Index: Yang, Yihua; Liu, Shouxin; Li, Junzhang; Tian, Xia; Zhen, Xiaoli; Han, Jianrong Synthetic Communications, 2012 , vol. 42, # 17 p. 2540 - 2554

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Citation Number: 7

Abstract

Reduction of compounds bearing CN double bonds, such as oximes, imines, and hydrazones, to amines is one of the most widely used and valuable functional group transformations in organic synthesis. [ 1 1. Zhu , Q.-C. ; Hutchins , RO ; Hutchins , MK Asymmetric reductions of carbon-nitrogen double bonds: A review . Org. Prep. Proc. Int. 1994 , 26 , 193 – 236 . [Taylor & Francis Online], [Web of Science ®] View all references ] Two approaches are ...