Synthetic communications

Efficient and Mild Procedure for Reductive Methylation of Amines Using N??Methylpiperidine Zinc Borohydride

H Alinezhad, M Tajbakhsh, R Zamani

Index: Alinezhad, Heshmatollah; Tajbakhsh, Mahmood; Zamani, Reza Synthetic Communications, 2006 , vol. 36, # 23 p. 3609 - 3615

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Citation Number: 15

Abstract

Abstract A simple and efficient procedure for reductive methylation of primary and secondary amines using N??methylpiperidine zinc borohydride (ZBNMPP), giving tertiary amines, is described. The reaction is carried out in methanol at room temperature under neutral conditions.