Copper??Catalyzed Intramolecular Oxidative C H Functionalization and C N Formation of 2??Aminobenzophenones: Unusual Pseudo??1, 2??Shift of the Substituent …

PC Huang, K Parthasarathy…

Index: Huang, Pang-Chi; Parthasarathy, Kanniyappan; Cheng, Chien-Hong Chemistry - A European Journal, 2013 , vol. 19, # 2 p. 460 - 464

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Citation Number: 28

Abstract

Highly-substituted acridones are versatile building blocks for many naturally occurring products and have attracted much attention due to their unique biological activities.[1] They are important antileishmanial, antifungal, antitumor, and DNA-intercalating anticancer drugs.[1d] The classical routes to the synthesis of acridones rely on the acid-induced ring- closure of N-phenyl anthranilic acids,[2a–c] oxidation of the corresponding acridinium ...