Design and syntheses of novel N′-((4-oxo-4H-chromen-3-yl) methylene) benzohydrazide as inhibitors of cyanobacterial fructose-1, 6-/sedoheptulose-1, 7- …

…, F Yi, Y Sha, YL Ren, MW Ding, LL Feng, J Wan

Index: Tu, Qi-Dong; Li, Ding; Sun, Yao; Han, Xin-Ya; Yi, Fan; Sha, Yibamu; Ren, Yan-Liang; Ding, Ming-Wu; Feng, Ling-Ling; Wan, Jian Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 11 p. 2826 - 2831

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Citation Number: 19

Abstract

Cyanobacterial fructose-1, 6-/sedoheptulose-1, 7-bisphoshatase (Cy-FBP/SBPase) is an important target enzyme for finding inhibitors to solve harmful algal bloom (HAB). In this study, as potential inhibitors of Cy-FBP/SBPase, a series of novel chromone-connecting benzohydrazone compounds (Novel N′-((4-oxo-4H-chromen-3-yl) methylene) benzohydrazide) were designed and synthesized. Their inhibitory activities against Cy- ...

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