e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Semisynthetic penicillins. I. 2-biphenylylpenicillins

JRE Hoover, AW Chow, RJ Stedman…

Index: Hoover,J.R.E. et al. J. Med. Chem., 1964 , vol. 7, # 3 p. 245 - 251

Full Text: HTML

Citation Number: 18

Abstract

The preparation of a number of penicillins with 2-biphenylyl side chains is described. Some of the substituted 2-biphenylcarboxylic acids used as intermediates were synthesized for the first time or were prepared by new methods. These penicillins were active against penicillin<;-resistant as well as penicillin G-susreptible staphylococci.

3'-Amino-[1,1'-biphenyl]-2-carboxylic acid Structure

3'-Amino-[1,1'-...

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3'-HYDROXY-[1,1'-BIPHENYL]-2-CARBOXYLIC ACID Structure

3'-HYDROXY-[1,1...

Aethyl-4-methyl-2-biphenylcarboxylat Structure

Aethyl-4-methyl...

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5-methyl-2-phenylbenzoic acid Structure

5-methyl-2-phen...

3-METHYLBIPHENYL-2-CARBOXAMIDE Structure

3-METHYLBIPHENY...

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3-METHYL-[1,1'-BIPHENYL]-2-CARBOXYLIC ACID Structure

3-METHYL-[1,1'-...

3-METHYLBIPHENYL-2-CARBONITRILE Structure

3-METHYLBIPHENY...

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3-METHYL-[1,1'-BIPHENYL]-2-CARBOXYLIC ACID Structure

3-METHYL-[1,1'-...

N-(2-cyano-3-methylphenyl)acetamide Structure

N-(2-cyano-3-me...

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3-METHYL-[1,1'-BIPHENYL]-2-CARBOXYLIC ACID Structure

3-METHYL-[1,1'-...

benzene Structure

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3-METHYL-[1,1'-BIPHENYL]-2-CARBOXYLIC ACID Structure

3-METHYL-[1,1'-...

9H-Fluoren-9-one,2,7-difluoro- Structure

9H-Fluoren-9-on...

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5-fluoro-2-(4-fluorophenyl)benzoic acid Structure

5-fluoro-2-(4-f...

N/A Structure

Dimethyl sulfate Structure

Dimethyl sulfate

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5-methoxy-2-phenyl-benzoic acid Structure

5-methoxy-2-phe...

Methyl-3-chlor-2-biphenylcarboxylat Structure

Methyl-3-chlor-...

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3-CHLORO-[1,1'-BIPHENYL]-2-CARBOXYLIC ACID Structure

3-CHLORO-[1,1'-...

N/A Structure

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3-CHLORO-[1,1'-BIPHENYL]-2-CARBOXYLIC ACID Structure

3-CHLORO-[1,1'-...

5-Fluoro-2-biphenylcarbonitrile Structure

5-Fluoro-2-biph...

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5-FLUORO-[1,1'-BIPHENYL]-2-CARBOXYLIC ACID Structure

5-FLUORO-[1,1'-...

5-Aminobiphenyl-2-carbonitrile Structure

5-Aminobiphenyl...

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5-FLUORO-[1,1'-BIPHENYL]-2-CARBOXYLIC ACID Structure

5-FLUORO-[1,1'-...

5-nitro-biphenyl-2-carbonitrile Structure

5-nitro-bipheny...

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5-FLUORO-[1,1'-BIPHENYL]-2-CARBOXYLIC ACID Structure

5-FLUORO-[1,1'-...

9H-Fluoren-9-one,1-fluoro- Structure

9H-Fluoren-9-on...

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3'-fluoro-biphenyl-2-carboxylic acid Structure

3'-fluoro-biphe...

N/A Structure

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3-FLUORO-[1,1'-BIPHENYL]-2-CARBOXYLIC ACID Structure

3-FLUORO-[1,1'-...