Substituted tetralins IV: Synthesis and stereochemistry of 4, 4??disubstituted 1, 2, 3, 4??tetrahydro??2??naphthoic acids

EM Kandeel, LJ Anderson, JH Block…

Index: Kandeel; Anderson; Block; White; Martin Journal of pharmaceutical sciences, 1972 , vol. 61, # 8 p. 1231 - 1234

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Abstract

Substituted Tetralins IV: Synthesis and Stereochemistry of 4,4-Disubstituted 1,2,3,4-Tetrahydro -2-naphthoic ... EZZAT M. KANDEEL, LERAY J. ANDERSON, JOHN H. BLOCK*, ALLEN I. WHITE, and ARNOLD R. MARTIN' ... Abstract 0 The syntheses of four 4-methyl-4-phenyl-l,2,3 ,4-tetra- hydro-Znaphthoic acids are described. The stereospecific cyclization of the cis-isomers and proton NMR studies establishing cistrans product ratios are also reported. ...