A convenient synthesis of azetidine-2-thiones and azetidin-2-imines

J Marchand-Brynaert, M Moya-Portuguez…

Index: Marchand-Brynaert, Jacqueline; Moya-Portuguez, Manuel; Huber, Isabelle; Ghosez, Leon Journal of the Chemical Society, Chemical Communications, 1983 , # 15 p. 818 - 819

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Citation Number: 10

Abstract

Azetidin-2-iminium salts, which are readily available from tertiary amides, can be easily converted into the corresponding thiones or imines. ... In spite of the amount of research into the synthesis of /?-lactams (l), very few papers have been devoted to the preparation of the thioxo and imino (3)5-9 analogues. We report here a general method for the synthesis of azetidine- ... 2-thiones and azetidin-2-imines from the readily available azetidin-2-iminium salts (4). Compounds ...

~97%

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