Microwave assisted Willgerodt-Kindler reaction of styrenes

FM Moghaddam, M Ghaffarzadeh…

Index: Moghaddam, Firouz Matloubi; Ghaffarzadeh, Mohammad; Dakamin, Mohammad G. Journal of Chemical Research - Part S, 2000 , # 5 p. 228 - 229

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Citation Number: 20

Abstract

The classical Willgerodt reaction involves heating an aryl alkyl ketone with ammonium polysulfide in a sealed vessel and results in formation of a thioamide with the same number of carbon atoms.1,2 Reaction times of several hours are com- mon and high pressure is caused by H2S formation. The oper- ational pressure difficulties could be eliminated by the Kindler modification of the reaction, ie. performing the reaction in a primary or secondary amine at ...