Chemistry and physics of lipids

Synthesis and tandem mass spectrometry of chlorinated triacylglycerols

AM Lefsay, RD Guy, A Chatt, RL White

Index: Lefsay, Abir M.; Guy, Robert D.; Chatt, Amares; White, Robert L. Chemistry and Physics of Lipids, 2013 , vol. 174, p. 55 - 63

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Abstract

Abstract The incorporation of 9, 10-dichlorooctadecanoyl groups using enzyme-catalyzed acylation and protecting group strategies yielded specific regioisomers of di-and tetrachlorinated triacylglycerols. Hexachloro-and hexabromotriacylglycerols were synthesized by addition of chlorine or bromine to tri-(cis-9-octadecenoyl) glycerol. Upon electrospray ionization and tandem mass spectrometry, the sodium adduct ions of all ...