Organic letters

Direct lactone formation by using hypervalent iodine (III) reagents with KBr via selective CH abstraction protocol

T Dohi, N Takenaga, A Goto, A Maruyama, Y Kita

Index: Dohi, Toshifumi; Takenaga, Naoko; Goto, Akihiro; Maruyama, Akinobu; Kita, Yasuyuki Organic Letters, 2007 , vol. 9, # 16 p. 3129 - 3132

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Citation Number: 52

Abstract

Lactones are the basic structural unit of natural products and are of great importance in the areas of pharmaceuticals, agrichemicals, flavor components, material, and polymer productions, and also are as well versatile building blocks for these applications. 1 In particular, certain aryl-substituted γ-lactones show a variety of significant biological behaviors. 2 One of the convenient and attractive routes for the synthesis of these lactones is the direct oxidative C−O coupling reaction ...