RSC Advances

Synthesis, characterization, antimicrobial, anticancer, and antituberculosis activity of some new pyrazole, isoxazole, pyrimidine and benzodiazepine derivatives …

P Palanisamy, SJ Jenniefer, PT Muthiah…

Index: Palanisamy, Pandaram; Jenniefer, Samson Jegan; Muthiah, Packianathan Thomas; Kumaresan, Sudalaiandi RSC Advances, 2013 , vol. 3, # 42 p. 19300 - 19310

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Citation Number: 8

Abstract

In an attempt to find a new class of antimicrobial, anticancer, and antituberculosis agents, a series of pyrazole, isoxazole, pyrimidine and benzodiazepine derivatives containing thiochromeno and benzothiepino moieties were prepared via the reaction of diketoester 2 and 11 with appropriate chemical reagents. Single crystal XRD studies have been done on compounds 3 and 12. All compounds were evaluated for antimicrobial, anticancer, and ...