HYPOGLYCAEMIC AGENTS. PART III

DF Hayman, V Petrow…

Index: Hayman,D.F. et al. Journal of Pharmacy and Pharmacology, 1962 , vol. 14, p. 522 - 533

Full Text: HTML

Citation Number: 4

Abstract

OUR work on hypoglycaemic agents is extended herein to some new variants of I-butyl-3-p- toluenesulphonylurea (I; R= Me, R'= S02* NH* C0. NHB~):(a) 1-Cyclohexyl-3-p- fluorobenzenesulphonyl-and 3-p-fluorobenzenesulphonyl-1-phenyl-urea (I; R= F, R= SO,. NH. CO-NH-cyclohexyl or Ph) have been prepared by reaction of the appropriate isocyanate with the sodium salt of p-fluorobenzenesulphonamide in aqueous acetone. The ...