Palladium??Catalyzed Cascade Reaction of α, β??Unsaturated Sulfones with Aryl Iodides

P Mauleon, AA Nunez, I Alonso…

Index: Mauleon, Pablo; Nunez, Angel A.; Alonso, Ines; Carretero, Juan C. Chemistry - A European Journal, 2003 , vol. 9, # 7 p. 1511 - 1520

Full Text: HTML

Citation Number: 56

Abstract

Abstract Unlike traditionally used acyclic 1, 2-disubstituted alkenes, the reaction of α, β- unsaturated phenyl sulfones with aryl iodides under Heck reaction conditions (Pd (OAc) 2 as catalyst, Ag 2 CO 3 as base in DMF at 120 0 C) takes place mainly by a cascade process, involving one unit of the alkene and three units of the aryl iodide, to afford a substituted 9- phenylsulfonyl-9, 10-dihydrophenanthrene. The dominant formation of this 3: 1 coupling ...