Studies on polypeptides XXXII: Solid??phase synthesis of RNase S??peptide 1??14 analogues; replacement of histidine??12 by β??(2??pyridyl)??L??alanine and β??(4??pyridyl) …

…, J Raap, W Bloemhoff, KET Kerling

Index: Hoes, C.; Raap, J.; Bloemhoff, W.; Kerling, K. E. T. Recueil: Journal of the Royal Netherlands Chemical Society, 1980 , vol. 99, # 3 p. 99 - 104

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Citation Number: 14

Abstract

Abstract The synthesis of two analogues of the N-terminal tetradecapeptide of ribonuclease A (RNase S-peptide 1-14), in which the active site histidine-12 residue is replaced by β-(2- pyridyl)-L-alanine and β-(4-pyridyl)-L-alanine, has been accomplished by the solid-phase method.