Abstract Aminomethylation with Mannich reagents derived from secondary amines and paraformaldehyde under improved conditions has been used to convert non-α-tocopherol homologues into α-tocopherol, the biologically most important vitamin E compound. Mono- and bis (aminomethylated) β-, γ-and δ-tocopherol were then subsequently transformed into the corresponding tocopherols (α-and β-tocopherol) by reductive deamination. As an ...
