e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

TBAF-Catalysed silver oxide-mediated cross-coupling of functional trimethysilylpyridines: access to arylpyridines and bihetaryl compounds

F Louërat, H Tye, S Napier, M Garrigou…

Index: Organic and Biomolecular Chemistry, , vol. 9, # 6 p. 1768 - 1773

Full Text: HTML

Citation Number: 6

Abstract

... Chem., 2011, 9, 1768-1773 Show Compounds Show Chemical Terms. ... and stability issues, these species have been scarcely used in heterocyclic chemistry especially in ... Indeed, the organic tetrabutylammonium cation (TBA + ) is known to greatly enhance the nucleophilicity of ...

3-Bromopyridine Structure

3-Bromopyridine

4-Chloro-2-trimethylsilylpyridine Structure

4-Chloro-2-trim...

~0%

3,3'-Bipyridyl Structure

4-chloro-2,3'-bipyridine Structure

4-chloro-2,3'-b...

3-Bromopyridine Structure

3-Bromopyridine

4-Chloro-2-trimethylsilylpyridine Structure

4-Chloro-2-trim...

~0%

Bromothiophene Structure

3,3'-Bipyridyl Structure

Detail

3-Bromopyridine Structure

3-Bromopyridine

4-Chloro-2-trimethylsilylpyridine Structure

4-Chloro-2-trim...

~13%

3,3'-Bipyridyl Structure

4,4'-Dichloro-2,2'-bipyridine Structure

4,4'-Dichloro-2...

Detail

4-Chloro-2-trimethylsilylpyridine Structure

4-Chloro-2-trim...

~5%

4-chloropyridine Structure

4-chloropyridine

4,4'-Dichloro-2,2'-bipyridine Structure

4,4'-Dichloro-2...

4-Iodobenzotrifluoride Structure

4-Iodobenzotrif...

4-Chloro-2-trimethylsilylpyridine Structure

4-Chloro-2-trim...

~16%

4-chloro-2-[4-(trifluoromethyl)phenyl]pyridine Structure

4-chloro-2-[4-(...

4,4'-Dichloro-2,2'-bipyridine Structure

4,4'-Dichloro-2...

3-Bromopyridine Structure

3-Bromopyridine

4-Chloro-2-trimethylsilylpyridine Structure

4-Chloro-2-trim...

~19%

4,4'-Dichloro-2,2'-bipyridine Structure

4,4'-Dichloro-2...

4-chloro-2,3'-bipyridine Structure

4-chloro-2,3'-b...

3-Bromopyridine Structure

3-Bromopyridine

4-Chloro-2-trimethylsilylpyridine Structure

4-Chloro-2-trim...

~26%

Bromothiophene Structure

3,3'-Bipyridyl Structure

Detail

3-Bromopyridine Structure

3-Bromopyridine

4-Chloro-2-trimethylsilylpyridine Structure

4-Chloro-2-trim...

~60%

3,3'-Bipyridyl Structure

4,4'-Dichloro-2,2'-bipyridine Structure

4,4'-Dichloro-2...

Detail

3-Bromopyridine Structure

3-Bromopyridine

4-Chloro-2-trimethylsilylpyridine Structure

4-Chloro-2-trim...

~47%

Bromothiophene Structure

3,3'-Bipyridyl Structure

Detail

4-Chloro-2-trimethylsilylpyridine Structure

4-Chloro-2-trim...

~91%

4-chloropyridine Structure

4-chloropyridine

4,4'-Dichloro-2,2'-bipyridine Structure

4,4'-Dichloro-2...

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Highly efficient monophosphine-based catalyst for the pallad...

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Palladium-catalyzed inter-and intramolecular coupling reacti...

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Tetraphosphine/palladium-catalyzed Suzuki–Miyaura coupling o...

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Amine-bridged bis (phenol) ligands for efficient Pd-catalyze...

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