Journal of heterocyclic chemistry

General preparative route to benzo [g] quinolines (1??azaanthracenes)

AP Krapcho, TP Gilmor

Index: Krapcho, A. Paul; Gilmor, Timothy P. Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 2 p. 445 - 452

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Citation Number: 7

Abstract

Abstract A convenient synthetic pathway to benzo [g] quinolines (1-azaanthracenes) has been developed. The nickel catalyzed coupling of methyl 2-chloronicotinate (3a) with benzylic organo zinc reagents 2a-e led to the methyl 2-benzylic substituted nicotinates 4a- ...