Kinetic resolution of terminal epoxides via highly regioselective and enantioselective ring opening with TMSN3. An efficient, catalytic route to 1, 2-amino alcohols

JF Larrow, SE Schaus…

Index: Journal of the American Chemical Society, , vol. 118, # 31 p. 7420 - 7421

Full Text: HTML

Citation Number: 230

Abstract

... Journal of Organic Chemistry (1995), 60 (15), 4884-92CODEN: JOCEAH ; ISSN:0022-3263. (American Chemical Society). A series of enantiomerically pure 4-substituted bis(oxazolines) I (R3 = Et, isobutyl; R4 = benzyl, iso-Pr, tert-Bu, triphenylmethyl, etc.) was prepd. ...