New 7??substituted quinolone antibacterial agents. The synthesis of 1??ethyl??1, 4??dihydro??4??oxo??7??(2??thiazolyl and 4??thiazolyl)??3??quinolinecarboxylic acids

TP Culbertson, JM Domagala…

Index: Journal of Heterocyclic Chemistry, , vol. 24, # 6 p. 1509 - 1520

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Citation Number: 20

Abstract

... strongly influenced by substituents at the 7-position, especially by nitrogen con- taining heterocycles [1]. Broad ... Y = H) [2]. Limited reports on quinolones have described vari- ous five membered heterocyclic substituents at ... d, J = 3) [p] 9.33 (S) 8.46 (d, J = 10) 9.21 (d, J = 6) 3.30 ( ...