Journal of the American Chemical Society

Displacements and Nuclear Substitutions on Hydroxypyrazines

G Karmas, PE Spoerri

Index: Karmas; Spoerri Journal of the American Chemical Society, 1956 , vol. 78, p. 4071,4076

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Citation Number: 24

Abstract

A variety of.'-li?. drt) sypS-raziiies has been broiiiinateti and phenylated, and three have beeii iiitrated. It Iias lieen found that halogens and nitro groups ortho to hydroxyl are easily displaced by acidic reagents, and such reactions afford convenieiit syntheses of dihalo-and dihydroxypyrazines.