The Ritter reaction under truly catalytic Brønsted acid conditions

…, JM Álvarez??Gutiérrez, F Rodríguez

Index: Sanz, Roberto; Martinez, Alberto; Guilarte, Veronica; Alvarez-Gutierrez, Julia M.; Rodriguez, Felix European Journal of Organic Chemistry, 2007 , # 28 p. 4642 - 4645

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Citation Number: 40

Abstract

Abstract Simple organic acids like 2, 4-dinitrobenzenesulfonic acid (DNBSA) catalyze the Ritter reaction of secondary benzylic alcohols giving rise to the corresponding N- benzylacetamides in usually high yields. Reactions can be conducted without exclusion of oxygen and without the need of dry solvents. With tertiary α, α-dimethylbenzylic alcohols a different pathway involving a formal dimerization reaction takes place under the acid- ...